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Outcomes of arthroscopic coracoclavicular management for acromioclavicular joint injuries: A systematic review
⁎Corresponding author: Moin Khan. khanmm2@mcmaster.ca
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Received: ,
Accepted: ,
This article was originally published by Reed Elsevier India Pvt. Ltd. and was migrated to Scientific Scholar after the change of Publisher.
Abstract
Abstract
Various surgical procedures for coracoclavicular (CC) ligament repair have been described for symptomatic acromioclavicular joint dislocations, with none emerging as a clear gold standard. There has been increased interest in arthroscopic approaches. This systematic review evaluates clinical outcomes after arthroscopic surgeries used to treat chronic and acute AC joint dislocations.
We searched three databases (PubMed, EMBASE, and OVID [MEDLINE]) from database inception to December 20, 2022. Studies were included if they met the following criteria: studies evaluating humans, English language studies, level of evidence I to IV, and studies investigating clinical outcomes in patients following arthroscopic surgery for coracoclavicular ligament reconstruction. Studies on open reconstruction techniques only were excluded. Primary outcomes included function/pain scores, coracoclavicular distances, complications, and revision rates.
Fifty-two studies were included. In 33 studies, postoperative Constant-Murley scores ranged from 82.8 to 99 points. Postoperative VAS scores ranged from 0.3 to 4.1 in 16 studies. In 46 studies, revision rates ranged from 0 % to 44.4 %. We did not observe a difference in revision rates between chronic and acute cases (P = 0.268). Complications were more common in chronic than acute cases (25.5 % vs. 16.4 %; P < 0.001).
Arthroscopic surgery for chronic and acute CC ligament injuries exceeds the MCID and PASS for several outcomes, with low failure rates. Arthroscopic CC reconstruction is a safe and effective alternative for chronic AC joint dislocations.
IV (Systematic Review of Level I-IV Studies)
Keywords
Arthroscopy
Coracoclavicular
Reconstruction
Outcomes
Systematic review
1 Introduction
Acromioclavicular (AC) joint dislocations can result in disruption of the AC ligament, coracoclavicular (CC) ligament, and deltopectoral fascia, depending on severity of injury.3 The Rockwood classification system identifies six grades of injury, considering the integrity of the AC and CC ligaments, direction of clavicular dislocation, and clavicular attachment with the deltoid and trapezius muscles.22 The current consensus for managing AC joint dislocations recommends non-operative management of Rockwood I and II injuries, while types IV, V, and VI are generally treated surgically.4 Type III injuries are typically managed nonoperatively; however, conservative treatments do not achieve active reduction of the dislocation, and studies have found that patients may experience long-term chronic pain and degeneration of the AC joint without surgery, particularly in horizontally unstable injury patterns.31 Therefore, some have advocated surgical treatment for type III injuries in young, active patients.
Surgical management of AC joint dislocations is dependent on chronicity of injury; while there are various techniques to maintain reduction of acute AC joint injuries (ORIF with hook plate, ORIF with tight rope, Bosworth screw, etc), chronic dislocations generally require reconstruction of the CC ligaments with allograft augmentation.19 Several studies have demonstrated the important role of the CC ligaments in stabilizing the AC joint, and as a result, procedures for CC ligament reconstruction have been developed.39
Traditionally, open surgical procedures were most common; however, arthroscopic techniques for the management of CC ligament injuries have been developed with the advancement of arthroscopy in recent years.50 Advantages of arthroscopic techniques including improved visualization, decreased soft tissue stripping and invasiveness, and the access to find and manage concomitant glenohumeral injuries that are often found in more severe dislocations.38
Transitioning from open to arthroscopic techniques for surgical procedures often can entail a learning curve and it is important to ensure that techniques remain safe and effective without compromising patient outcomes.75,76 Data studying the learning curve for surgeons when transitioning from open to arthroscopic Latarjet technique for recurrent shoulder dislocations is instructive. In a systematic review, Ekhtiari et al. observed that the most commonly reported difference was that surgeons earlier in the learning curve needed longer operative times.18 However, other factors like complication rates, patient-reported outcomes, and technical characteristics such as screw angle and graft position did not differ based on experience. The same thorough analysis of the literature on arthroscopic CC ligament reconstruction is lacking.
This systematic review evaluates clinical outcomes following arthroscopic management of acute and chronic CC ligament injuries to determine its effectiveness and safety in treating symptomatic AC joint dislocations.
2 Methods
2.1 Search strategy
We searched three databases (PubMed, Ovid Medline, and EMBASE) for articles discussing arthroscopic coracoclavicular ligament reconstruction published from database inception to December 20, 2022. The search was performed using the terms: “acromioclavicular joint injury,” “acromioclavicular joint separation,” “shoulder separation,” “arthroscopic coracoclavicular ligament reconstruction,” “arthroscopic coracoclavicular reconstruction,” “arthroscopic coracoclavicular,” and “coracoclavicular ligament reconstruction.”
2.2 Study screening
Two reviewers performed study screening for the titles, abstracts, and full-text articles independently and in duplicate. Study screening was performed per PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-analyses) guidelines. In the instance of disagreement during the title and abstract screenings, articles were moved onto the next stage for further review. In the full-text screening, any disagreements were resolved by a senior author.
2.3 Assessment of study eligibility
Both our research question and study eligibility criteria were determined a priori. The following inclusion criteria was used: English language studies, studies evaluating humans, level of evidence I to IV, and studies investigating clinical outcomes in patients following arthroscopic surgery for coracoclavicular ligament reconstruction. Studies on open reconstruction techniques only were excluded. Review articles, book chapters, commentaries, technique papers, animal studies, and case series with <5 patients were also excluded.
2.4 Data abstraction and statistical analysis
Two reviewers collected the data, which was stored using Microsoft Excel (Version 2019, Microsoft, Redmond, WA, USA). Basic data regarding the article included author information, year published, study design, and study sample sizes. Sex ratios, mean age, mean follow-up in months, and details of surgical management were collected. A variety of shoulder-specific outcome measures were included, such as the American Shoulder and Elbow Surgeons (ASES), Constant-Murley (CMS), Subjective Shoulder Value (SSV), and University of California at Los Angeles (UCLA) Shoulder scores. Visual Analog Scale (VAS) and 36-Item Short Form Survey scores were also utilized. Scores specific to the acromioclavicular joint were also evaluated, including Acromioclavicular Joint Instability (ACJI) and Taft Scores (TS). The ACJI score was described by Scheibal et al. as an acromioclavicular joint specific outcome measure.59 The ACJI is graded out of 100 total points encompassing five categories: radiological evaluation (35 points), function (25 points), pain (20 points), cosmesis (10 points), and activities of daily living (10 points). The Taft Score was developed to score results following both conservative and surgical management of AC joint dislocations and has a maximum score of 12 points that includes subjective, objective, and radiologic criteria.68
Additionally, post-operative revision rates, complications data, and coracoclavicular distances (CCD) measured at rest and using stress views were reported. Data was collected for various time points in patient care and grouped accordingly when relevant.
Descriptive statistics were collected, including means, standard deviations, proportions, ranges, and 95 % confidence intervals (CI). Additionally, when preoperative and postoperative data was available for patient-reported scores, mean percent (%) differences were calculated. For complications and revision rates, a subgroup analysis was performed between chronic and acute AC joint injuries (CC ligament reconstruction versus arthroscopic reduction internal fixation). Pooling of final follow-up scores was planned in acute and chronic cohorts. Outcomes will be reported as means, with standard deviation/standard error measurements, in >1 studies. Unpaired t-tests will be used to identify differences between chronic and acute cohorts, with an a priori level of significance at P < 0.05. We attempted a similar analysis for graft vs. no graft procedures; however, the data did not allow for this since almost all chronic cases were reconstructed with graft, while acute cases had variable constructs used. As a result, the chronic vs. acute analysis is comparable to graft vs. no graft.
2.5 Study quality assessment
Studies included in our review were assessed using the MINORS instrument, which was designed to evaluate the quality of non-randomized, comparative and non-comparative studies.66 The highest score on the MINORS checklist is 16 for non-comparative studies and 24 for comparative studies. For randomized controlled trials, the Cochrane risk of bias tool was utilized to determine study quality.25 There are 8 types of bias evaluated by the Cochrane tool; namely: allocation concealment, blinding of personnel/participants, blinding of the data analyst, blinding of the outcome evaluation, selective reporting, incomplete outcome data, random sequence generation, and “other” biases.
2.6 Assessment of agreement
A kappa (κ) statistic was calculated to evaluate inter-reviewer agreement for the title, abstract, and full-text screening stages. The level of agreement was established a priori with the following guidelines: κ of 0.61 or greater was viewed to be “substantial” agreement; κ of 0.41–0.6 was determined to be “moderate” agreement; and κ/ICC of 0.20–0.40 was categorized as “slight” agreement.
3 Results
3.1 Study characteristics and demographics
A total of 52 studies were included in the final quantitative analysis, of which 2 were randomized controlled trials, 15 were cohort studies, 34 were case series studies, and 1 was a case control study (Fig. 1).1–45,46–77 In noncomparative studies, the average MINORS score was 12.0 (ranging from 10 to 14). In comparative studies, the average MINORS score was 17.2 (ranging from 15 to 20). All studies were clear in their aims, appropriately included of patients, had an a priori established plan for data collection, and created adequate endpoints. Only one study (2 %) had blinding of endpoints, while 94 % of studies had appropriate follow-up periods, and 56 % of studies had a loss to follow-up of less than 5 %. No studies prospectively calculated the study size needed to detect a difference in outcomes. The evaluations of study bias performed for RCTs included in this review are outlined in Table 2 and they were of overall moderate quality. In the evaluation of agreement between reviewers, κ was 0.41 for the title screening, 0.61 for the abstract screening, and 0.87 for the full-text screening.

| Authors (Year) | Study Design | MINORS Score | Number of Patients | % Male | Age (Years) | Follow-Up (Months) | Rockwood InjuryClassification |
| Chernchujit et al. (2006) | Case Series | 12 | 13 | 84.6 % | 40.2 | 18 | 6 IV, 7 V |
| Murena et al. (2009) | Case Series | 12 | 16 | 93.8 % | 33.3 | 31 | 10 III, 4 IV, 2 V |
| Boileau et al. (2010) | Case Series | 12 | 10 | 80.0 % | 41.0 | 12.8 | 3 III, 5 IV, 2 V |
| Salzmann et al. (2010) | Case Series | 11 | 23 | 91.3 % | 37.5 | 58 | 3 III, 3 IV, 17 V |
| Defoort et al. (2010) | Cohort Study | 18 | Group 1: 9Group 2: 7a | 87.5 % (Overall Cohort) | 39.6 (Overall Cohort) | 17 (Overall Cohort) | Group 1: 2 III, 7 IVGroup 2: 4 III, 3 IV |
| Scheibel et al. (2011) | Case Series | 11 | 28 | 92.9 % | 38.8 | 26.5 | 28 V |
| Yoo et al. (2011) | Case Series | 12 | 13 | 76.9 % | 28.4 | 17 | 3 III, 10 V |
| El Sallakh (2012) | Case Series | 11 | 11 | 90.9 % | 26.0 | N/A | 3 IV, 8 V |
| Cook et al. (2012) | Case Series | 12 | 9 | 100.0 % | 25.9 | 9.7 | 2 III, 7 IV |
| Milewski et al. (2012) | Case Series | 11 | 10 | 80.0 % | 31.4 | 5.3 | 2 III, 8 V |
| Jensen et al. (2013) | Case Series | 10 | 16 | 87.5 % | 40 | 13 | 11 III, 5 V |
| Kraus et al. (2013) | Cohort Study | 18 | Group 1: 15Group 2: 13a | Group 1: 93.3 %Group 2: 92.3 % | Group 1: 37.7Group 2: 40.9 | 24 (Overall Cohort) | Group 1: 15 V |
| Jensen et al. (2014) | Cohort Study | 18 | Group 1: 26Group 2: 30a | Group 1: 88.5 %Group 2: 93.3 % | Group 1: 39Group 2: 39 | Group 1: 17Group 2: 48 | Group 1: 10 III, 16 VGroup 2: 12 III, 18 V |
| Liu et al. (2015) | Case Series | 12 | 12 | 66.67 | 48.0 | 24 | 7 III, 5 V |
| Shin et al. (2015) | Case Series | 12 | 18 | 94.44 | 45.4 | 25.6 | 3 III, 1 IV, 14 V |
| Parnes et al. (2015) | Case Series | 12 | 12 | 100.00 | 25.0 | 30.4 | 12 V |
| Loriaut et al. (2015) | Case Series | 11 | 39 | 66.67 | 35.7 | 42.3 | 28 III, 11 IV |
| Clavert et al. (2015) | Case Series | 12 | 116 | 82.76 | 37 | N/A | 56 III, 35 IV, 25 V |
| Chaudhary et al. (2015) | Case Series | 12 | 17 | 88.2 % | 35.0 | 22.1 | 6 III, 1 IV, 10 V |
| Singh et al. (2016) | Case Series | 12 | 9 | 88.9 % | 38.4 | 22.8 | 4 III, 2 IV, 2 V, 1Fracture |
| Faggiani et al. (2016) | Cohort Study | 17 | Group 1: 8Group 2: 8a | 93.8 % (Overall Cohort) | 36.9 (Overall Cohort) | 13.0 (Overall Cohort) | Group 1: 4 III, 4 IVGroup 2: 4 III, 4 IV |
| Takase et al. (2016) | Case Series | 12 | 22 | 86.4 % | 38.1 | 38 | 22 V |
| Tauber et al. (2016) | Cohort Study | 18 | Group 1: 12Group 2: 14 | 92.3 % (Overall Cohort) | Group 1: 41.3Group 2: 51.3 | Group 1: 27.1Group 2: 31.2 | Group 1: 3 III, 4 IV, 5 VGroup 2: 3 III, 1 IV, 10 V |
| Cisneros et al. (2017) | Cohort Study | 17 | Group 1: 20Group 2: 12Group 3: 10Group 4: 11a | Group 1: 85.0 %Group 2: 100.0 %Group 3: 100.0 %Group 4: 100.0 % | Group 1: 36Group 2: 31Group 3: 41Group 4: 41 | N/A | Group 1: 3 III, 3 IV, 14 VGroup 2: 3 III, 2 IV, 7 VGroup 3: 1 III, 1 IV, 8 VGroup 4: 5 III, 6 V |
| Shin et al. (2017) | Case Series | 11 | 21 | 95.2 % | 41.1 | 27.2 | 7 III, 14 V |
| Zhang et al. (2017) | Case Series | 11 | 24 | 87.5 % | 28.7 | 39.5 | 8 III, 16 V |
| Lee et al. (2017) | Case Series | 12 | 47 | 74.5 % | 37 | N/A | 15 III, 2 IV, 30 V |
| Hann et al. (2018) | Case Series | 11 | 34 | 85.3 % | 43.3 | 26.4 | 34 V |
| Bin Abd Razak et al. (2018) | Case Control | 20 | 16 | 93.8 % | 41.4 | 23 | N/A |
| Issa et al. (2018) | Case Series | 11 | 19 | 84.2 % | 34.4 | 76.9 | 15 III, 4 IV |
| Athar et al. (2018) | RCT | N/A | 24 | 4.2 % | 42.6 | N/A | 16 III/IV, 8 V |
| Xu et al. (2018) | Cohort Study | 18 | Group 1: 39Group 2: 39 | Group 1: 76.9 %Group 2: 71.8 % | Group 1: 29.4Group 2: 31.2 | >2 years | Group 1: 39 IVGroup 2: 39 IV |
| Stein et al. (2018) | Cohort Study | 19 | Group 1: 29Group 2: 27a | Group 1: 96.6 %Group 2: 96.3 % | Group 1: 34.2Group 2: 37.7 | N/A | Group 1: 8 III, 1 IV, 20 VGroup 2: 3 III, 4 IV, 20 V |
| Hashiguchi et al. (2018) | Case Series | 12 | 12 | 100.0 % | 40.8 | 106.3 | 8 III, 4 V |
| Jobmann et al. (2019) | Case Series | 12 | 55 | N/A | 35.2 | >6.5 months, >16.0 months | N/A |
| Lee et al. (2019) | Case Series | 12 | 27 | 74.1 % | 35.2 | 27.2 | 12 III, 15 V |
| Kraus et al. (2019) | Cohort Study | 15 | Group 1: 14Group 2: 13a | Group 1: 21.4 %Group 2: 46.2 % | Group 1: 47.2Group 2: 44.9 | Group 1: 24.3Group 2: 28.8 | 2 II, 19 III, 17 V (Overall Cohort) |
| Lim et al. (2019) | Case Series | 12 | 18 | 66.7 % | 47 | 17 | 10 V, 3 III, 5 Neer IIb |
| Boileau et al. (2019) | Case Series | 12 | 57 | 86.0 % | 42 | 36 | 11 III, 19 IV, 27 V |
| Thangaraju et al. (2019) | Case Series | 12 | 20 | 100.0 % | 40 | 4.5 | 20 IV/V |
| Abdelrahman et al. (2019) | RCT | N/A | 22 | 68.2 % | 31 | 24 | 16 III, 6 IV |
| Seo et al. (2019) | Cohort Study | 18 | Group 1: 11Group 2: 21 | Group 1: 100.0 %Group 2: 79.2 % | Group 1: 47.2Group 2: 51.6 | Group 1: 13.6Group 2: 13.7 | N/A |
| Çarkçı et al. (2020) | Cohort Study | 17 | Group 1: 27Group 2: 9 | Group 1: 88.9 %Group 2: 88.9 % | Group 1: 29.9Group 2: 32.6 | Group 1: 32.1Group 2: 29.3 | 14 III, 22 V |
| Lamplot et al. (2020) | Case Series | 11 | 88 | 89.8 % | 39.6 | 73.2 | 32 III, 56 V |
| Campagna et al. (2021) | Case Series | 14 | 41 | 85.4 % | 31.3 | 35 | 33 III, 8 V |
| Yoo et al. (2021) | Cohort Study | 19 | Group 1: 12Group 2: 10a | Group 1: 66.7 %Group 2: 70.0 % | Group 1: 42.8Group 2: 44.4 | Group 1: 30.1Group 2: 33.8 | Group 1: 5 III, 7 VGroup 2: 5 III, 5 V |
| Voss A et al. (2021) | Cohort Study | 17 | Group 1: 15Group 2: 15a | Group 1: 100.0 %Group 2: 100.0 % | Group 1: 31.9Group 2: 33.5 | 24.7 (Overall Cohort) | Group 1: 6 IV, 9 VGroup 2: 10 IV, 5 V |
| Murphy et al. (2021) | Case Series | 11 | 23 | 87.0 % | 41 | 26 | 3 III, 2 IV, 18 V |
| Li et al. (2021) | Case Series | 11 | 48 | 81.3 % | 43.8 | 39.3 | 5 IV, 43 V |
| Nie et al. (2021) | Cohort Study | 20 | Group 1: 28Group 2: 84a | Group 1: 78.6 %Group 2: 78.6 % | Group 1: 35.9Group 2: 36.0 | Group 1: 33.1Group 2: 32.9 | Group 1: 2 III, 16 V, 10 VGroup 2: 4 III, 46 IV, 34 V |
| Nolte et al. (2021) | Case Series | 12 | 102 | 90.2 % | 45.0 | 56.4 | 49 III, 8 IV, 45 V |
| Marsalli et al. (2021) | Cohort Study | 14 | 102 | 95.0 % | 37.3 | 20.8 weeks | 102 V |
| Authors (Year) | Random Sequence Generation | Allocation Concealment | Blinding of Participants and Personnel | Blinding of Outcome Assessment | Blinding of Data Analyst | Incomplete Outcome Data | Selective Reporting | Other Bias |
| Athar et al. (2018) | High | Unclear | High | Unclear | Unclear | Low | Low | Low |
| Abdelrahman et al. (2019) | Low | Low | High | High | Unclear | Low | Low | Low |
Sample sizes in included studies ranged from 8 to 116 individuals. The age of patients ranged from 18 to 70. The percentage of male patients ranged from 4.2 % to 100 %. The final follow-up of the included studies ranged from 0.5 to 128 months (See Table 1 for details).
3.2 Surgical techniques
Regarding surgical technique, 40 studies utilized beach chair positioning, 3 studies used lateral decubitus positioning, 4 used other modified positioning, and 5 did not report positioning. Two arthroscopic portals were used in 20 studies, 3 portals in 24 studies, and 4+ portals in 2 studies. Six articles did not report the number of portals used.
Thirty-eight studies reported the surgical management of acute AC joint injuries, while 10 evaluated reconstructions following chronic injuries. Four studies reported data from both acute and chronic injuries.
In 43 cohorts evaluating arthroscopic management of acute injuries, common surgical constructs included TightRope fixation (n = 25 studies), EndoButton constructs (n = 7), DogBone/Fiberwire/Tigerwire cortical buttons (n = 6), and others (n = 5). In 12 chronic injury cohorts, surgical constructs were GraftRope fixation (n = 3), Single EndoButton and Double-Button constructs (n = 2), tenodesis screws (n = 4), ZipTight fixation (n = 1), TightRope fixation (n = 1), and anchors (n = 1). Almost all chronic reconstructions used a graft along with the aforementioned constructs to reproduce the CC ligaments. Out of the 12 chronic injury cohorts, 6 exclusively used autografts for reconstruction of the CC ligaments, 2 used allografts, 3 used either allograft or autograft, and 1 did not use grafting.
The majority of patients underwent surgery for injuries of Rockwood classification III, IV, or V. The breakdown of injury classification varied between studies (See Table 1 for details).
3.3 Summary of primary outcome variables
Postoperative ACJI scores taken at the final follow-up were reported in 5 studies, ranging from 58.4 to 89.5 points (Table 3). Scores were ≥84.5 points in 4 of 7 total cohorts.
| Outcome Score | # of Studies (# of Cohorts) | # of Chronic vs.Acute Cohorts | Follow-UpRange (Months) | Postoperative Score Range | Range in Chronic Cohorts | Range in Acute Cohorts |
| Acromioclavicular Joint Instability | 5 (7) | 3 Chronic4 Acute | 24.0 to 31.2 | 58.4 to 89.5 | 58.4 to 89.5 | 75.9 to 87.0 |
| American Shoulder and Elbow Surgeons | 7 (8) | 2 Chronic5 Acute1 Chronic + Acute | 13.6 to 54.6 | 86.3 to 96.6 | 88.0 to 95.3 | 86.3 to 95.7 |
| Constant-Murley Scores | 32 (36) | 6 Chronic30 Acute | 13.0 to 76.9 | 82.8 to 99.0 | 84.0 to 96.0 | 82.8 to 99 |
| SF-36 Physical Component | 3 (5) | 1 Chronic3 Acute1 Chronic + Acute | 24.0 to 56.4 | 56.2 to 59.6 | 59.6 | 56.2 to 58.3 |
| SF-36 Mental Component | 2 (4) | 1 Chronic3 Acute | >24.0 | 51.1 to 56.6 | 56.6 | 51.1 to 56.2 |
| Subjective Shoulder Value | 11 (13) | 6 Chronic7 Acute | 12.8 to 36.0 | 78.0 to 95.0 | 78.0 to 95.0 | 90.0 to 96.2 |
| Taft Score | 10 (12) | 4 Chronic8 Acute | 13.0 to 31.2 | 9.0 to 11.1 | 9.0 to 11.0 | 10.0 to 11.1 |
| UCLA Shoulder | 6 (6) | 1 Chronic5 Acute | 12.8 to 39.5 | 16.5 to 31.7 | 16.5 | 28.4 to 31.7 |
| Visual Analog Scale | 16 (17) | 2 Chronic15 Acute | 13.0 to 76.9 | 0.3 to 4.1 | 0.6 to 4.1 | 0.3 to 1.8 |
The ASES score was reported in 7 studies with 8 cohorts, of which 2 included both preoperative and postoperative measurements. Scores at final follow-up ranged from 86.3 to 96.6 points. Mean percentage difference was only evaluated in one study (31.45 %), since the other articles including preoperative scores only provided median values.
Constant-Murley scores were measured in 32 studies with 36 cohorts, of which 15 included preoperative comparison values. CMS values at final follow-up ranged from 82.8 to 99 points, with 22 studies having scores ≥90 points. Ten studies had average postoperative scores ≥95 points. The average difference between pre- and post-operative scores ranged from 11.2 to 69.5 (mean % change from 15.8 % to 408.8 %). Nine studies found mean improvements >100 %. Two studies measured CMS scores across four time points: 1) preoperatively, 2) at 6 months, 3) at 12 months, and 4) at 24 months. Salzmann et al. demonstrated improvement from 27.45 points preoperatively to 85.79 at 6 months, 93.34 at 12 months, and 95.31 at 24 months.58 Stein et al. showed improvement from 34.5 points preoperatively to 89.0 at 6 months, 93.9 at 12 months, and 94.3 at 24 months.67
Postoperative SF-36 Physical Component scores were reported in 3 studies with 5 cohorts. Scores ranged from 56.2 to 59.6. In 2 studies, the mean difference between pre- and final post-operative scores were 14.4 (mean % change: 34.3 %) and 9.5 (mean % change: 20.6 %).
In 2 studies with 4 cohorts, final SF-36 Mental Component scores ranged from 51.1 to 56.6. The mean difference between pre-operative and final post-operative scores was only calculated in one study, measuring at 1.8 points (3.7 %).
Final postoperative SSV scores were reported in 11 studies with 13 cohorts. Six cohorts included preoperative values. Preoperative scores ranged from 32.9 to 72.3. Final postoperative scores ranged from 78.0 to 95.0, and 9 studies had postoperative values ≥ 90 points. Mean differences between pre-operative and final postoperative scores ranged from 20.1 to 62.1 points (mean % difference ranged from 27.9 % to 194.1 %). Two studies showed % difference improvements greater than 100 % (129.2 % and 194.1 %).
In 10 studies with 12 cohorts, final Taft scores ranged from 9.0 to 11.1. Preoperative scores were reported in 3 studies and ranged from 3.1 to 9.2. The mean difference between pre-operative and final post-operative scores was reported in these 3 studies and ranged from 1.9 to 7.8 (mean % change ranged from 20.7 % to 251.6 %).
Final follow-up UCLA Shoulder scores were included in 6 studies and ranged from 16.5 to 31.7. Four studies had average scores ≥30 points. In 3 studies, the mean difference between preoperative and final postoperative UCLA Shoulder scores ranged from 12.9 to 22.3, with mean % changes from 75.9 % to 237.2 %.
In 16 studies with 17 cohorts, final postoperative VAS scores ranged from 0.3 to 4.1. Sixteen cohorts (94.1 %) had final VAS scores ≤2, and 7 (41.2 %) had scores ≤0.6. In 10 cohorts, preoperative VAS scores ranged from 4.2 to 8.3. The mean difference between pre-operative and final post-operative VAS scores ranged from −3.2 to −7.5 (mean % change ranged from −70.5 % to −94.1 %).
In 51 studies with 56 cohorts and 1550 patients, a total of 277 complications (17.8 %) were reported. Of the 277 complications, the most reported were coracoid/clavicle tunnel widening (N = 68, 24.5 %), recurrent vertical/horizontal instability (N = 57, 20.6 %), hardware failures (N = 48, 17.3 %), infections (N = 23, 8.3 %), coracoid/clavicular fractures (N = 14, 5.1 %), and intraoperative complications (N = 14, 5.1 %). In 43 total cohorts with 1173 patients who experienced acute injuries, a total of 192 complications (16.4 %) were recorded. In 12 chronic injury cohorts with 306 patients, 78 complications (25.5 %) were observed. A chi-squared test of independence showed that patients undergoing arthroscopic surgery for chronic injuries were more likely to experience complications than counterparts with acute injuries, χ2 (1, N = 1448) = 13.5, p < 0.001. The most common complication in acute cases was coracoid/clavicle tunnel widening (N = 48, 27.1 %), followed by hardware failure (N = 35, 19.8 %), recurrent vertical/horizontal instability (N = 29, 16.4 %), infections (N = 15, 8.5 %), coracoid/clavicle fractures (N = 7, 4.0 %), and intraoperative complications (N = 4, 2.3 %). The remaining 54 complications (28.1 %) were not identified in these categories. In chronic cases, horizontal/vertical instability was the most common complication (N = 26, 33.3 %), followed by coracoid/clavicle tunnel widening (N = 16, 20.5 %), hardware failure (N = 8, 10.3 %), infections (N = 7, 9.0 %), coracoid/clavicle fractures (N = 5, 6.4 %), and intraoperative complications (N = 3, 3.9 %). The remaining 13 complications did not fall in these categories (16.7 %). On chi-square analysis, there was a significant difference in the types of complications experienced by acute vs. chronic cases, χ2 (6, N = 270) = 13.5, p = 0.01.
In 44 studies with 48 cohorts and 1357 patients, revision rates ranged from 0 % to 44.4 %. Twenty-six cohorts (54.2 %) did not report any patients needing revision surgery. A further 6 cohorts (12.5 %) had revision rates ≤5 %, and 9 (18.4 %) had rates <8 %. Across all studies, 76 patients (5.6 %) required revision surgery. In 34 acute injury cohorts with 969 patients, there were 43 total revisions (4.4 %). In 11 chronic injury cohorts with 263 patients, 16 revisions were reported (6.1 %). There was no difference between groups, χ2 (1, N = 1232) = 1.2, p = 0.268.
Coracoclavicular distances were measured using rest views in 7 studies and stress views in 5 studies. At rest, mean preoperative CCD ranged from 13.5 to 29.1 mm (mm). Distances measured immediately after the operation was performed ranged from 5.7 to 11.4 mm, and final follow-up values ranged between 7.3 and 11.8 mm. In five studies reporting both pre- and final post-operative CCD, the mean difference ranged from −4.6 to −17.3 mm, with % differences from −28.8 % to −59.7 %. In studies using stress views, CCD values ranged between 16.1 and 31.9 mm. Final measurements ranged from 10.5 to 16.9 mm, with mean differences from −5.6 to −15.0 mm (% differences from −33.0 % to −50.0 %).
Loss of reduction (LOR) information was provided in 46 studies with 49 cohorts and 1326 patients. Rates of LOR ranged from 0.0 % to 88.9 %. Across all studies, a total of 216 patients (16.3 %) experienced postoperative loss of reduction. There was substantial variation in the definitions and severity of LOR (see Table 4 for a detailed breakdown).
| Loss of Reduction Definition | # of Cases (% of All LOR Cases) |
| Loss of reduction >2 mm | 19 (9.9 %) |
| Loss of reduction >3 mm | 10 (4.6 %) |
| Loss of reduction >5 mm | 17 (7.9 %) |
| Loss of reduction >8 mm | 8 (3.7 %) |
| Loss of reduction between 2 and 4 mm | 10 (4.6 %) |
| Loss of reduction between 4 and 8 mm | 12 (5.6 %) |
| 25 % increase in CCD | 23 (10.6 %) |
| 50–100 % increase in CCD | 4 (1.9 %) |
| >100 % increase in CCD | 2 (0.9 %) |
| Defined as “slight” loss of reduction | 3 (1.4 %) |
| Defined as “partial” loss of reduction | 14 (6.5 %) |
| Subluxation | 19 (8.8 %) |
| Complete redislocation | 25 (11.6 %) |
| Unclear | 50 (23.1 %) |
Comparison of Acute vs. Chronic Cohorts Final Follow-Up Scores:
The Acromioclavicular Joint Instability score was only pooled from 2 chronic cohorts, with a combined value of 71.6±14.3. There was insufficient data to pool from studies reporting on acute injuries.
A total of 4 acute cohorts reported average postoperative ASES scores with measures for error, with a final pooled score of 92.4±7.5. In 2 chronic cohorts, the final pooled score was 91.7±9.0.
Postoperative Constant-Murley scores were pooled from 17 acute cohorts, with a final value of 92.3±3.8. In comparison, the pooled final Constant-Murley scores in 3 chronic cohorts was 92.4±5.6.
The SF-36 physical component score was reported in 3 acute cohorts, with a pooled value of 57.6±2.2. In 1 chronic cohort, the final SF-36 physical score was 59.6±2.0 (P = 0.309). In 3 acute cohorts, the pooled SF-36 mental component score was 54.2±4.6. In 1 chronic cohort, the SF-36 mental score was 56.6±1.9.
In 2 acute cohorts, the pooled postoperative SSV score was 93.9±6.5. Comparatively, the final SSV score was a bit lower at 84.9±10.9 in 4 total chronic cohorts.
The UCLA Shoulder score was pooled from 3 acute cohorts, with a final value of 31.1±3.2. This was higher than the one study reporting a chronic group, which had an average postoperative score of 16.5±1.8.
Postoperative Taft Scores were pooled from 3 studies reporting acute injuries, with a combined value of 10.9±1.2. In comparison, 2 studies reporting chronic injury data had a pooled score of 10.0±1.8.
Postoperative Visual Analog Scale scores were pooled from 12 total acute cohorts, with a final combined value of 1.0±1.1. The pooled VAS score was 2.4±1.4 in 2 chronic cohorts.
4 Discussion
This systematic review presents a comprehensive overview of the literature evaluating clinical and patient-reported outcomes following arthroscopic management of symptomatic CC ligament injuries after AC joint dislocations. The most important finding in this review is that arthroscopic procedures for CC injuries result in substantial improvements in both clinical and patient-reported outcome measures and overall low revision rates.
The Constant-Murley Score (CMS) was the most frequently measured in studies evaluating surgical outcomes after arthroscopic CC reconstruction. Postoperative CMS scores in our study ranged from 82.8 to 99 and can be compared with published data for various open techniques. A systematic review by Moatshe et al. evaluating different techniques for open AC and CC ligament reconstruction found that postoperative CMS scores ranged from 76.4 to 96.0 for free tendon graft, 82.6 to 97.8 for suspensory devices, 85.9 to 97.0 for synthetic ligament devices, 81 to 96 in modified Weaver-Dunn, and 83.0 to 94.6 for hook plate/K-wires techniques.51 Though our analysis does not directly compare CMS scores after arthroscopic and open reconstruction, our findings were similar to the existing literature studying different open techniques for CC reconstruction.
All studies in this review evaluating CMS scores both preoperatively and postoperatively showed substantial improvements, according to quantified estimates for both minimal and substantial clinical benefits (SCB). Studies have estimated the MCID for the CMS score following rotator cuff injuries, with Louwerens et al. identifying values of 9.8 (with a mean change method) and 5.5 (using receiver operating characteristic analysis).44 The same study found a SCB of 19.9, using the mean change method, and 10.5, based on receiver operating characteristic analysis. Similarly, Kukkonen et al. identified an MCID threshold of 10.4 in patients with rotator cuff injuries.34 Included studies in this review showed improvements greater than all previous estimates of MCID in CMS scores. However, it is important to note that no work has previously identified MCID cutoffs for CMS scores after AC joint injuries specifically.
The Visual Analog Scale was used to measure preoperative and postoperative pain in 15 studies.17 Estimates for interpreting VAS scores have suggested that ratings between 0 and 0.4 cm reflect no pain, 0.5–4.4 cm indicate mild pain, 4.5–7.4 cm are moderate pain, and 7.5–10 cm mean severe pain 28. In our study, all postoperative VAS scores indicated that patients had either no pain or mild pain. Previous studies have estimated MCID between preoperative and postoperative VAS scores, however, none have found values specific to AC joint injuries. A recent study by Tashjian et al. estimated the MCID in VAS scores after arthroscopic rotator cuff repair to be 2.4 cm, while previous work by the same authors showed a MCID of 1.4 cm.70,71 In their first study, the authors also identified a Patient Acceptable Symptomatic State (PASS) score at 3 cm. A study performed by Menendez et al. recently determined a MCID value of 1.7 cm and PASS of 2.5 cm in patients undergoing the Latarjet procedure.47 This review found across all studies that arthroscopic CC reconstruction results in improvements in VAS scores that surpassed both MCID and PASS values described in the literature for shoulder pathologies.
The Subjective Shoulder Value, which is expressed as a percentage of function compared with a healthy shoulder (which would score 100 %), was another commonly reported score. Nine out of 11 studies had final postoperative SSV scores ≥90 points, reflecting almost entirely healthy function compared with uninjured shoulders. A previous study by Van de Water et al. used two different methods to estimate a MCID for SSV scores in a cohort of patients with proximal humeral fractures, finding values of 12.1 and 26.6.74 All 6 cohorts saw improvements in SSV scores greater than 12.1, while 4 cohorts had changes in SSV larger than 26.6.
In the included studies, a wide range of complication rates were noted, likely reflecting variation in the arthroscopic techniques being performed as well as heterogeneous criteria for complications between studies. The complication rates can be compared with the open-CC reconstruction data provided in the systematic review by Moatshe et al. which found rates of 10.3 %, 6.2 %, 4.4 %, 12.8 %, and 26.3 % for free graft reconstruction, suspensory devices, ligament advanced reinforcement systems, coracoacromial ligament transfers, and hook plate/k-wires, respectively. Most studies in our review showed similarly low complication rates, suggesting a comparable safety profile of arthroscopic CC reconstruction procedures.
Revision rates were low in most included studies, with a majority of cohorts having no reported revisions (56.25 %) or rates ≤5 % (10.4 %). These revision rates can be compared with data in the existing literature, with the work by Moatshe et al. again being instructive.51 In their systematic review on open CC reconstruction, the authors found unplanned reoperation rates of 0.9 %, 1.2 %, 2.8 %, 2.6 %, and 5.4 % in synthetic ligament devices, free tendon graft, suspensory devices, hook plate/K-wires techniques, and modified Weaver-Dunn, respectively. Although a few studies on arthroscopic CC reconstruction did show higher revision rates than currently described, the majority were comparable to the existing literature on open techniques.
When comparing adverse events between acute and chronic injuries, we found a greater incidence of complications in chronic injury cohorts, while there was no difference in revision rates. There may be several reasons for why chronic cases experienced a greater rate of complications. First, chronic patients typically have more scar tissue and bone callus, making the arthroscopic dissection more difficult. Second, chronic cases are performed with graft reconstruction, which is a more involved procedure than acute fixation, requiring more dissection and a longer operative time. Additionally, grafting itself has inherent risk, since autografts are associated with donor site morbidity and allografts carry an inherent infection risk. When comparing the types of complications experienced, chronic cases appeared to have greater rates of hardware failure, while acute injuries more frequently experienced recurrent instability.
In our pooled analysis, there appeared to be little differences between acute and chronic injury cohorts in postoperative scores for several outcomes, such as the ASES, CMS, SF-36 (physical and mental components), and Taft score. However, pooled scores for the chronic cohorts in SSV, UCLA Shoulder score, and VAS appeared to be worse overall than for acute counterparts. It must be noted that this finding is only based on a descriptive interpretation of the data, as there were not enough studies to identify statistically significant differences. Our subanalysis is also limited by a lack of preoperative data to compare % improvements.
At final follow up after arthroscopic CC ligament reconstruction, coracoclavicular distances measured at rest ranged from 7.3 mm to 11.8 mm, showing marked improvement from preoperative values. In healthy individuals, the average distance between the clavicle and coracoid process ranges between 11 and 13 mm.37 Thus, arthroscopic CC ligament reconstruction was effective at restoring and maintaining coracoclavicular distances to within a normal range. However, loss of reduction (LOR) did occasionally occur and rates varied greatly between studies, potentially reflecting differences in the arthroscopic techniques utilized. Loss of reduction is among the most common complications after CC reconstruction. Lee et al. found that LOR after CC reconstruction was associated with prolonged duration between injury and treatment and poorer quality initial reduction.36 Additionally, the authors suggested that failed reduction is associated with a more medial position of clavicle tunnels. Other studies have similarly reported that more medial bone tunnels are associated with unsuccessful reduction after reconstruction.10,15,45,59 This emphasizes the importance of developing a clear visual field when working arthroscopically by removing any excess soft tissue and adequately visualizing your tunnel placement.
4.1 Strengths
To our knowledge, this systematic review is the first to comprehensively study clinical outcomes following arthroscopic CC ligament reconstruction. Our analysis included a large sample of 52 total studies, spanning a variety of arthroscopic techniques for CC ligament reconstruction across many institutions. A rigorous methodology was performed for study screening and analysis according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.56
4.2 Limitations
This analysis has several limitations. Since arthroscopic CC reconstruction has gained interest relatively recently, the majority of studies include smaller samples and shorter follow-up timelines. There is also limited data regarding the learning curve of the procedure, and how results may vary as surgeons become more familiar with the technique. Additionally, several studies included in our analysis were early pioneers in arthroscopic CC reconstruction, and the techniques described may have been improved upon in recent years. Thus, the overall effect size of outcomes may potentially be underestimated in this study. Due to a limited number of studies reporting mean/standard deviation scores for most outcomes, our comparative analysis of postoperative scores between acute and chronic cases was limited to a descriptive analysis. There were insufficient papers reporting the same outcomes to allow for assessment of statistically significant differences between acute and chronic cases. Lastly, there are limited high quality directly comparative studies examining open versus arthroscopic CC ligament reconstruction to determine with confidence if one technique is superior.
5 Conclusions
This systematic review demonstrates that arthroscopic management of acute and chronic CC ligament injuries exceeds the MCID and PASS for a variety of clinical outcomes, with low failure rates. Arthroscopic CC reconstruction is a safe and effective alternative to open surgery for chronic AC joint dislocations. Future, high-quality randomized studies are needed to directly compare outcomes between open and arthroscopic surgery for CC ligament injury to determine superiority of one technique.
Guardian/patient consent
Not applicable.
Declarations of interest
Dr. Khan is a consultant for Arthrex and Bioventus, and receives research support from Arthrex and Smith+Nephew. Dr. Erickson is a consultant for Arthrex, and receives research support from Arthrex, DePuy, Linvatec, Stryker, and Smith+Nephew.
Ethics
Our study was IRB-exempt as it is a systematic review and evaluates only publicly available studies.
Funding
This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.
CRediT authorship contribution statement
Rohan Shah: Conceptualization, Formal analysis, Investigation, Project administration, Visualization, Writing – original draft, preparation, Writing – review & editing. Chetan Gohal: Conceptualization, Methodology, Project administration, Supervision, Validation, Writing – original draft, preparation, Writing – review & editing. Mark Plantz: Data curation, Formal analysis, Investigation, Methodology, Software, Validation. Brandon J. Erickson: Supervision, Writing – review & editing. Moin Khan: Conceptualization, Methodology, Project administration, Supervision, Writing – original draft, preparation, Writing – review & editing. Vehniah Tjong: Conceptualization, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing.
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